人口老化是目前全球皆面臨的問題，有機體的老化有部分成因來自於細胞層面的衰弱，又稱之為細胞老化。細胞老化的生物特徵，包括端粒長度縮短、端粒酶活性減少、生長與發炎因子的增加等，過去文獻發現運動訓練對於高齡者端粒長度的變化有所影響。本文針對阻力訓練對高齡者端粒長度、細胞老化指標與氧化壓力的影響相關研究進行文獻整理，發現許多研究皆呈現運動訓練對端粒長度具有保護的正面效果，但在阻力訓練的效果上仍未有一致的結論。本研究推論過去阻力訓練的研究介入大多是以低強度的阻力訓練為主，其訓練強度與頻率對身體的刺激與反應機制尚不明確。建議未來研究能與肌力與體能訓練專家學者研擬妥適針對高齡者阻力訓練的強度與機制，並同時檢測多項與老化相關之身體功能指標與認知能力指標，分析老化相關之生物指標與各項身體功能之相關性，使阻力訓練對於抗老化的效益更加明確。

Population aging is a global issue currently faced by societies worldwide. One of the contributing factors to organismal aging stems from cellular senescence, also known as cellular aging. Biological hallmarks of cellular aging include shortened telomere length, reduced telomerase activity, and increased growth and inflammatory factors. Previous literature has found that exercise training influences telomere length in older adults. This study reviews relevant literature regarding the impact of resistance training on telomere length, cellular aging markers, and oxidative stress in older adults. While many studies have shown that exercise training has a protective effect on telomere length, conclusions regarding the effects of resistance training remain inconsistent. This study suggests that past research interventions involving resistance training have predominantly utilized low-intensity regimens, and the effects of training intensity and frequency on the body's stimulation and response mechanisms are not yet clear. It is recommended that future research collaborate with experts and scholars in strength and conditioning to devise appropriate intensities and mechanisms for resistance training in the elderly population. Simultaneously, multiple physiological indicators related to aging and cognitive performance should be assessed to analyze the correlations between aging-related biological markers and various aspects of physical functionality. This approach aims to clarify the efficacy of resistance training in combating aging.

生長分化因子 15; 淋巴細胞; 身體活動

growth differentiation factor 15; lymphocyte; physical activity