目的：探討非肥胖成人經由運動與飲食控制，當體重減輕達兩公斤且體脂肪明顯下降時，是否伴隨胰島素敏感性的增加。方法：15位女性受試者參與試驗，接受運動訓練同時配合飲食控制作為減重計畫，所有受試者分別於實驗前（前測）與實驗後（後測），進行血液樣本收集，分析血糖、胰島素、胰島素敏感性指數與三酸甘油酯。結果：受試者減重達兩公斤時，前測與後測之血液胰島素濃度分別為7.45 ± 0.65 mU/l和6.57 ± 0.47 mU/l顯著降低（p < .05）；胰島素敏感性指數分別為7.86 ± 0.29、8.40 ± 0.25顯著增加（p < .05）。結論：減重的好方法是適度飲食控制同時加上運動，本研究結果發現非肥胖之成年人，體重減輕達原體重的3.58%，可有效地改善胰島素敏感性。

Purpose: To determine whether two kilogram body weight loss could improve whole body insulin sensitivity through exercise training and dietary control in non-obesity adults. Methods: Fifteen women subjects were recruited to complete weight loss project with exercise training and dietary control. All blood samples were collected for analysis in glucose, insulin, insulin sensitivity index and triglycerides before and after experiment period, respectively. Results: The insulin levels were shown significant decrease in two kilogram weight loss compared to prior to weight project (7.45 ± 0.65 mU/ l and 6.57 ± 0.47 mU/l, p < .05). Insulin sensitivity was significantly improved after finishing weight loss project (7.86 ± 0.29 and 8.40 ± 0.25, p < .05). Conclusions: Dietary control with exercise training simultaneous is a good method for weight loss in non-obese adults. Weight loss up to 3.58% of the original weight could significantly improve whole body insulin sensitivity.

運動; 胰島素; 胰島素阻抗

exercise; insulin; insulin resistance