本研究目的為探討三天登山活動對荷爾蒙濃度與胰島素敏感度的影響。方法：以十七名健康的男性為受試對象（年齡：28.70±1.26歲；BMI：22.28±0.56 kg/平方公尺），於攀登武陵四秀（活動區域海拔為2200~3400公尺）前後檢測葡萄糖耐受度(oral glucose tolerance test, OGTT)、胰島素敏感度、血清可體松、睪固酮、生長激素、紅血球生成素、脫氫異雄固酮及腫瘤壞死因子α等生理指標。結果：三天登山活動後可提升葡萄糖耐受度與胰島素敏感度，顯著增加血清睪固酮、可體松、紅血球生成素及腫瘤壞死因子α濃度(p<.05)，脫氫異雄固酮則顯著降低(p<.05)。顯示三天登山活動對生理產生影響，為適應登山的壓力，體內透過荷爾蒙變化調節生理反應。結論：本研究發現三天登山活動可提升葡萄糖耐受度與胰島素敏感度，此效應可能與荷爾蒙濃度改變有關。

The present study was to investigate the effects of three-day mountain climbing on hormone level and insulin sensitivity. Ten non-obesity and prime-age males (age 28.70±1.26 yrs, BMI 22.28±0.56 kg/m^2) were participated in this study. Oral glucose tolerance test (OGTT) was performed on the pre-and three-day of mountain Wu-Ling climbing (altitude 2200-3400 m). Fasting blood samples before OGTT were taken for measuring serum cortisol, testosterone, growth hormone (GH), erythropoietin (EPO), DHEA-s and TNF-α level. The results of this study appeared that three-day mountain climbing improved glucose tolerance and insulin sensitivity, significantly elevated serum testosterone, EPO, TNF-α level, and decreased DHEA-s. In conclusion, three-day mountain climbing improved glucose tolerance and insulin sensitivity, and this improvement was associated with changed hormone level.

葡萄糖耐受度; 脫氫異雄固酮; 腫瘤壞死因子α; 紅血球生成素

Glucose tolerance; DHEA-s; TNF-α; EPO